This medication is an anti-microtubule agent, prescribed for Hodgkins lymphoma, lung cancer, breast cancer, head and neck cancer, and testicular cancer. It slows or stops the growth of cancer cells in the body.
How does Vinblastine work:
Vinblastine harms cancer cells causing their death.
How should Vinblastine be used:
It comes as a solution for injection to be administered by a healthcare provider into the vein. Adult- IV- Initial: The recommended dose is 3.7 mgm2, body surface area (bsa). It may be increased if needed. Maximum: 18.5 mgm2week.
Common side effects of Vinblastine :
Chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. Low white blood cell count. High blood pressure. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Not hungry. Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative. Mouth and lip irritation. Using a soft toothbrush or cotton swabs and rinsing the mouth may help. Do not use mouth rinses that have alcohol in them. Hair loss. Hair most often grows back when this drug is stopped. Bone pain. May not be able to get pregnant.
What do I do if I miss a dose
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
What precautions should I take when taking Vinblastine :
If you have an allergy to vinblastine or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have an infection or an unsafe low white blood cell count. If you are pregnant or may be pregnant.
When do I need to seek medical help
Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. Any bruising or bleeding. Chest pain or pressure, a fast heartbeat, or passing out. Numbness or tingling in your hands or feet. Not able to pass urine. A big weight loss. Very hard stools (constipation). Very bad belly pain. Feeling very tired or weak. Shortness of breath. Very bad jaw pain. Very bad headache. Seizures. Any rash. Some side effects may happen up to 2 weeks after the shot. Report them to your doctor. Side effect or health problem is not better or you are feeling worse.
Can I take Vinblastine with other medicines:
Sometimes drugs are not safe when you take them with certain other drugs and food. – Taking them together can cause bad side effects. – Be sure to talk to your doctor about all the drugs you take.
Are there any food restrictions
Avoid alcohol and grapefruit juice.
How do I store Vinblastine :
Store it in refrigerator (2° to 8°C).
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.